WHAT IS OZONE? Ozone is a particular form of oxygen. There are molecules with two atoms in the normal atmospheric oxygen, but the ozone contains one oxygen molecule with three different values. So the ozone can be dissolved quickly about 15 times more than the oxygen in the blood. We have to introduce a right concentration in the body due that the effect of ozone administration at a smaller concentration could be ineffective and a higher concentration decrease the activity of antioxidant defence system and could possibly have harmful effects. Oxygen + Energy = OZONE More Oxygen in the cell means more Energy. THE IMPORTANCE OF OXYGEN Healthy cells in the body need and love oxygen. Most undesirable micro-organisms are anaerobic, which means that they thrive in the absence of oxygen; in fact, they are destroyed by the presence of oxygen. Organisms such as fungi, parasites, bacteria, and primitive viruses like HIV, Epstein Barr, Coxsackie and Cytomegalovirus are often associated with states of ill health. Note that conventional medicine blames these micro-organisms for many chronic illnesses. The body becomes deprived of adequate levels of oxygen through improper breathing, polluted air, inadequate nutrition and junk foods, and stress. This provides an anaerobic environment in which the micro-organisms thrive. Healthy cells which have sufficient oxygen and nutrients, manufacture an enzyme coating around themselves which protects them against invasion. Oxygen starved cells are unable to produce enough enzymes to fortify their cell walls; they subsequently become weaker and more vulnerable. In addition, cancer begins when a normal cell cannot get enough oxygen. If the level of available oxygen falls below 60%, a cancer response is triggered in the cells. In order to survive the cell begins to ferment sugar instead of burning it. This results in a greatly reduced energy output, which means that a proper enzyme coating cannot be maintained around the cell. The restriction on cell replication is inactivated, and the cell begins to make copies of itself wildly. Heat is continually generated through the chemical action of oxygen upon carbon, which releases carbon dioxide for elimination. If insufficient oxygen is present, carbon monoxide is produced instead. Carbon monoxide is an irritant to the nervous system, interferes with organ functions, reduces basal body temperature, and prevents oxygen uptake by the red blood cells. This has the effect of debilitating the body, thus making it susceptible to infection and disease. HOW DOES OZONE WORK? 1.- Inactivation of bacteria, viruses, fungi, yeasts and protozoa Ozone has been shown to destroy the outer shell of most micro- organisms, thereby penetrating the cell membrane and altering the DNA. Sophisticated organisms such as human cells have enzymes that can restabilise disrupted DNA, whereas primitive organisms do not have this protective capability. This is another mechanism by which ozone selectively targets disease causing micro-organisms, and spares healthy cells. Repeated treatments of ozone therapy are usually needed, because certain viruses and fungi are more susceptible at certain stages of their development. Some micro-organisms are much more resistant than others, and will require more treatment. The viruses that contain lipids are more sensitive to deactivation by ozone – Herpes, Mumps, Measles, Influenza, Rabies, HIV and the Chronic Fatigue producing viruses: Epstein Barr, Coxsackie and Cytomegalovirus. 2.- Stimulation of oxygen metabolism Ozone causes increased metabolism inside the red blood cells [increased 2,3-DPG], which releases more oxygen to the tissues. Ozone also stimulates the production of enzymes, which act as cell wall protectors and scavengers of free radicals. It enhances energy production in the cells by complex biochemical reactions. 3.- Formation of Peroxides When ozone is introduced into the body, it is broken down into free radical agents called peroxides. These have beneficial effects because they are attracted to weakened or diseased cells and react with lipids [fats] in the cell membrane. The enzymes in the healthy, intact cell wall prevent penetration by these peroxides. Thus the peroxides in ozone selectively attack only those cells which contain parasites, viruses etc, or are weakened by cancer or toxins. 4.- Enhancement of circulation In circulatory disease, a clumping of red blood cells hinders blood flow through the small capillaries and decreases oxygen uptake by the red blood cells due to reduced surface area. Ozone reduces or eliminates clumping, and restores flexibility thereby increasing oxygen carrying capacity. Improved viscosity of the blood also leads to better oxygenation of the tissues. Ozone oxidises the plaque in arteries, which unclogs and frees up the circulation. A vasodilator, Prostacycline, is also produced by ozone, which dilates the arteries. 5.- Dissolution of tumours Ozone inhibits cancer cell metabolism. In addition, ozone oxidises the outer lipid layer of cancer cells, thus destroying them. 6.- Activation of the immune system Optimal administration of medical ozone causes an increase in the production of interferon and interleukins, which launch an entire cascade of immunological reactions. 7.- Effect on medicines The potency of any medicine taken concurrently with ozone treatment is greatly increased. The unpleasant side effects of toxic, but necessary, medications such as chemotherapy can be greatly minimised by ozone therapy. WHAT CAN OZONE DO? Inactivates viruses, bacteria, yeasts, fungi and protozoa Stimulates the immune system Improves circulation, clearing arteries and veins Purifies blood and lymph Normalizes hormone and enzyme production Reduces inflammation Reduces pain and calms the nerves Prevents stroke damage Improves cardiac arrhythmias Improves brain function and memory Oxidises toxins, allowing their excretion Chelates heavy metals Prevents and reverses degenerative disease Prevents and treats communicable diseases Prevents and treats Autoimmune disease Increases the potency and minimizes the side effects of chemotherapy Assist in treatment of cancers, post viral Chronic Fatigue Syndromes, Autism, etc. FIELDS OF APPLICATION. INDICATIONS Surgery Abscesses, wound infection, septic conditions, peritonitis, decubitis, burns, badly healing wounds, trophic ulcers, chronic osteomyelitis, thrombophlebitis, arterial occlusive disturbances of the lower limbs, diabetic foot, purulent-destructive lung & pleura diseases, purulent arthritis, deformating arthrosis, cardio-surgical interferences, pre- and postoperative treatment. Internal medicine Chronic gastritis & gastroduodenitis, chronic colitis, peptic ulcer, chronic hepatitis, hepatocirrhosis, chronic bronchitis, bronchial asthma, rheumatic diseases, arthritis & arthrosis, ischemic heart disease, allergic diseases, diabetes mellitus Urology Chronic pyelonephritis, acute and chronic renal failure (nephrism), cystitis, diseases transmissible by sexual way, urethritis, prostatitis Neurology Ischemic apoplectic attack, cerebrovascular insufficiency, diseases of peripheral nervous system, migraine, disseminated sclerosis, compressive ischemic neuropathies, spinal osteochondrosis Obstetrics & Gynecology Inflammatory female genital diseases, bacterial vaginosis, vulvar dystrophy, gestosis, early toxicosis, fetoplacental insufficiency, pregnancy anemia, spontaneous & threatened abortion, prevention of intrauterine fetus infection, fatness-associated pregnancy complications, infertility Dermatology Furunculosis, pyoderma, herpes, mycosis, scleroderma, psoriasis, neurodermatitis, eczema, bullous dermatosis, acne, allergodermia, agiitis, lichen planus, pemphigus etc. Cosmetology Acne rash, cellulites, local lipodystrophy, alopecia, vascular defects, hypertrophic & keloid scars, age related changes Dentistry Caries lesions, hypersensitive teeth, cracked tooth syndrome, peri- apical lesions, gingival & periodontal diseases, post-extraction, post- extraction alveolitis, surgical procedures, peri-implantitis, soft-tissue lesions etc. Ophthalmology Blepharitis, pain syndrome, eversion of the eyelid, glaucoma, ischemia of the eye ground, cataract, keratitis, conjunctivitis, pemphigus, erosion of the cornea, ulcers of the retina, hordeolum etc. HOW IS IT ADMINISTERED? 1.- Intravenous therapy An intravenous line is inserted into a vein, and 100-150ml of blood is drawn into a sterile vacuum flask. Medical ozone is also inserted into the flask and when the two are rapidly mixed together, the blood turns a bright cherry red. This ozonated blood is now highly charged with oxygenating power, and fed back into the same vein. The whole procedure takes about 30 minutes. 2.- Vaginal, urethral or rectal insufflations Ozone is introduced into the vagina, urethra or rectum by means of a catheter. 3.- Autohaemotherapy 5-10 ml blood is withdrawn by syringe, mixed with ozone, and injected back into a deep muscle. 4.- External limb bagging A limb is covered with an airtight bag and ozone is introduced into the bag for 30-40 minutes. 5.- Ozonated olive oil Ozone is bubbled through olive oil continuously for 7 days. The resulting cream is very effective as a topical application in a wide variety of skin conditions. 6.- Intramuscular, Intra-articular & intradiscal O2/O3 gas injections. ARE THERE ANY PRECAUTIONS TO OBSERVE? To prevent any unwanted oxidative effects, it is best to take a good anti-oxidant combination for 7 days before starting intravenous ozone therapy. Ozone therapy is contraindicated in the following: Acute myocardial infarction, severe cardiovascular instability (block, Wolff-Parkinson-White), convulsive status, pregnancy, recent internal bleeding and blood coagulation disorder, severe anemia, hyperthyroidism, thrombocytopenia, cramp tendency, ozone allergy, chronic relapsing pancreatitis, alcoholic intoxication and Fauvism (a deficiency of the enzyme glucose-6-phosphate dehydrogenase). References Bocci, V. 2002. Oxygen-Ozone Therapy. A Critical Evaluation. Kluwer Academic Pub. Bocci, V. 2005. Ozone, A new medical drug. Springer Viehban-Haensler, R. 2002. The Use of Ozone in Medicine. 4th Ed. ODREI-Pub. Viebahn-Hänsler, R. Ozon-Sauerstoff-Therapie. Editorial Haug. 2009. Viebahn-Hänsler R. Hitos del ozono médico. Revista de la Sociedad Española del Dolor. Vol. 12. II. Editorial ARAN. 2005. 3-9. Menéndez Cepero S. A, González Álvarez Ricardo, Ledea Lozano O.E. et al. Ozono: Aspectos básicos y aplicaciones clínicas. Editorial CENIC.2008. Rovira G. La Ozonoterapia tópica en el manejo de úlceras flebostáticas dolorosas de más de seis meses de evolución. Rev. Soc. Esp. Dolor 12: Nº Extra II, 48-52, 2005. De Lucas J.C. Infiltración periférica con ozono. Indicaciones, técnicas y experiencia clínica. Revista de la Sociedad Española del Dolor. Vol.12.II. Editorial ARAN. 2005. 37-47. Hidalgo Tallón F.J. Oxígeno-ozonoterapia: una realidad médica. Revista de la Sociedad Española del Dolor. Vol.16. 3. Editorial ARAN. 2009. 190-191. Andreula C., Simonetti L., et al: Minimally Invasive Oxygen- Ozone Therapy for Lumbar Disk Herniation. AJNR Am J Neuroradiol 24: 996-1000, May 2003. Baeza J. Infiltración neuroaxial con ozono. Fisiopatología y mecanismos de acción. Revista de la Sociedad Española del Dolor. Vol.12. II. Editorial ARAN.2005. 18-23. Bocci V. Mecanismos de acción generales de la ozonoterapia y mecanismos en el tratamiento del dolor. Revista de la Sociedad Española del Dolor. Vol.12. II. Editorial ARAN. 2005.24-36. Borrelli e., Bocci V. A Novel Therapeutic Option for Crhonic Fatigue Syndrome and Fibromyalgia. Riv Ital Ossigeno-Ozonoterapia 1: 149-153, 2002 If you would like additional information regarding our services or to request an appointment, you can contact us by phone (952 80 53 68) or by email .